Title Essay Example

Title Essay Example Title Essay Title Essay 1. What is the application ZenMap GUI commonly utilized for? Portray a situation where you would utilize this kind of utilization. /Scanning all spaces inside the neighborhood area. /If I was a monetary bookkeeper, I would utilize this to perceive what my representatives are getting to and who is doing what on the organization web. I might want to discover who is trading off their benefits and getting to unseemly destinations. 2. What is the connection between dangers, dangers and vulnerabilities in accordance with Information Systems Security all through the seven spaces of a run of the mill IT foundation? /They all influence security and uprightness of a system space nearby. 3. Which application is utilized in sync #2 in the hacking procedure to play out a helplessness appraisal filter? /Nessus 4. Before you direct a moral hacking procedure or entrance test in a live creation arrange, what must you do preceding playing out the surveillance and examining and checking techniques? Play out an IP have revelation and port serious output 5. What is a CVE posting? Who hosts and who supports the CVE database posting site? /A framework that gives a record to freely know ISS powerlessness/The open 6. Could ZenMap GUI distinguish what working frameworks are available on IP servers and Workstations? What might that alternative resemble in the order line if running an output on 172. 30. 0. 10? /Yes/It would be the green content in the order line . In the event that you have examined a live host and identified that it is running Windows XP workstation OS, how might you utilize this data for playing out a Nessus Vulnerability evaluation filter? /You have to choose Windows Credentials in the drop down menu close to qualification type. 8. When powerlessness is recognized by Nessus, where would you be able to check for more data with respect to the distinguished weakness, misuses, and the hazard moderation

Internationa human rights law Essay Example | Topics and Well Written Essays - 1500 words

Internationa human rights law - Essay Example As a rule, the use of extraterritorial ward resolutions regularly gets important to control the direct of the state operators in another region if their behaviors affect the national interests of their nation of source (Ovey and Robin, 2006, p.25). As to global laws, there are situations where extraterritorial ward has been practiced past worldwide limits especially under understanding between the concerned gatherings or countries. These legitimate understandings permit the US government to practice authority and purview over the individuals from the US military in these nations. Numerous different nations have additionally sanctioned laws and consented to arrangements with different nations to permit them indict their residents in different nations for violations, for example, slaughter, cheats and atrocities among others. This is regularly polished whether or not the wrongdoings were submitted extraterritorially or in their homelands. For instance, the UK government has fused the Rome rule act into their local laws. This enactment permits criminal arguments to be documented against UK nationals who perpetrate wrongdoings in different nations. In such manner, such hoodlums can be arraigned by the measures of the UK laws regard less of whether their nations of habitations don't have such laws. Al-Skeini v. U.K was a case including the examination of a protest wherein the British soldiers had purportedly abused and slaughtered five Iraqi regular people and injured the 6th one. Thusly, the groups of the casualties looked for equity from the European Commission on human rights. One of the significant contentions encompassing the case was the topic of whether the case was inside the locale of the ECHR since violations were submitted outside the United Kingdom. Despite the fact that the past statute had consistently tried to confine the extraterritorial locale of the European nations in different regions they control, the ECtHR Grand Chamber courts decided that since the

How do I improve my TOEFL Writing Score

How do I improve my TOEFL Writing Score I get this question a lot. Heres what I think you should do:Get some templates for each essay type.Watch videos lectures on each question type.Read as many sample essays as possible.Take accurate practice tests.Improve your grammar.Get your practice essays graded.Details about how to do these things are below!Read My Guides (and Templates) for Each Writing TaskEverything I know about the writing sectioncan be found in my guides to the two tasks. Here they are:Writing the Integrated TOEFL EssayWriting the Independent TOEFL EssayNot only will these guides show you how to write the essays, but they will tell you how the questions are structured and the patterns to look out for.Check out My Video SeriesI have also made a bunch of YouTubevideos about this section. Heres the first:Read some Good Sample EssaysThe best way to internalize what you need to do on test day is to read as many strong sample essays as possible. Start with my personal collection. They are categorized by style, which will help you to understand how the question will actually be structured on test day.Get some Good Practice TestsYou absolutely need to get good practice tests and questions to answer. This will make you more familiar with the test.Getting good independent questions is easy. You can find those on my page.Getting good integrated questions is more difficult, but I recommend the following sources:The Official Guide to the TOEFL (but skip Test1)The Official iBT Test Collection Volume 1 (five good tests)The Official iBT Test Collection Volume 2 (five good tests)TSTPreps Test Pack (10 good tests, online) try the coupon code goodine10off for a discount.I dont recommend anything from:EdusynchBest My TestKaplanBarronsWork on Your GrammarI know, studying grammar really sucks. But it will make a different in the medium and long term. You should probably work with one of the following books:English Grammar in Use 5th EditionGrammar in Use Intermediate 4th Edition (same as the above, but Ameri can)Oxford Practice Grammar IntermediateIf you use the first book, you can pair it with my study guide.Get Your Practice Essays Corrected and ScoredOnce you actually start writing essays you can hire me to correct your mistakes and tell you how they would score. That costs about $19 bucks but it might help a lot. You can sign up over here. It looks a bit like this:

Hurricanes and Earthquakes - 1652 Words

Hurricanes and earthquakes are two of the most dangerous natural disasters in the United States. They can be very disastrous and deadly. In the United States, there have been 73 hurricanes since 1954. Earthquakes are harder to detect because they have to have at least a magnitude of 5 (Earthquakes per year, 2009). The amount of earthquakes detected in the United States was 1656 in the past 10 years (Earthquakes per year, 2009). The World Meteorological Organization is the organization that can choose the names of hurricanes. At the beginning of the year, the first hurricane always begins with an A name, and continue down the alphabet (NHC, 2003). The letters not used to name a hurricane are, Q, U, X, Y, and Z (Netting, 2003).†¦show more content†¦It can start at the top of the chain with the individual stories and trickle down through, environmental all the way to government. Catastrophic Disasters Caused by EarthquakesCatastrophic disaster can occur with little or no warning. They may cause significant personal or property loss, and there is a greater sense of danger and helplessness than in predictable disasters. Examples of catastrophic disasters are tornadoes, earthquakes, and hurricanes. However, under certain conditions, normally predictable events may turn into unpredictable, catastrophic events. Earthquakes take place on planet Earth annually. The majority of earthquakes are so slight that they are not even noticed. The powerful earthquakes can cause numerous destructions and take place on the planet nearly once in two weeks. Fortunately, the majority take place in the oceans that is why they are accompanied with the catastrophic consequences when, for example, the earthquake causes tsunami. On December 26, 2004, giant waves hit the Indonesian, and Indian Islands. One year after the tsunami tore across the Indian Ocean, the signs of devastation ar e still everywhere (Casey, 2005). The amount of environmental waste can be seen after the water had subsided. It is unfortunate that catastrophic events have to happen in order for humans to react.Show MoreRelatedNatural Disasters : A Natural Disaster It s A Major Concern For Every Human Earth981 Words   |  4 Pagesbe destroyed by floods, hurricanes, cyclones, twisters, avalanches, volcanic eruptions and a major earthquake. In case of tsunamis many fields will be saturated by salt water and will take years to grow any produce or crops again, with landslides and avalanches homes are beyond repair and will take many months to be repair. All your personal effects, vehicles, documentation will be lost forever because of the natural disaster. The major disaster in our planet Earthquakes – it’s a sudden releaseRead MoreEarthquake And Earthquakes Essay1032 Words   |  5 Pages 4. EXPLAIN THE RISK AND NATURAL HAZARDS EARTHQUAKES AND VOLCANIC ACTIVITIES. HOW CAN WE PLAN TO CONTROL THESE RISKS? Earthquakes and volcanoes have disastrous effects on humans and properties, it’s also very harmful for the environment overall including wildlife. Earthquakes cause a lot of damage due their shaking nature,they can further lead to tsunamis and most common hazard related to earthquakes is landsliding. The earthquake intensity is what measures the effects it has on land surface, andRead MoreNatural Disasters, A Study Of Events1596 Words   |  7 Pagesdescribe a hurricane, an earthquake and a mudslide. We will briefly discuss how, or if, our ancestors were able to predict and therefore mitigate loss of life or damage to infrastructure for these types of disasters 100 years ago. Then we will look at how our modern society is able to accomplish this in current times. Finally, we will cover how we could better predict future events and plan accordingly. We will explore the effects of Hurricane Andrew on Homestead, Florida, the 2010 earthquake on HaitiRead MoreEssay on Exploring Wh y Some Hazards Are Easier to Predict Than Others1018 Words   |  5 Pagesobservations or information. According to: - www.dpi.state.wi.us/standards/sciglos.html When looking at the different types of hazards to injure or kill people, or costing the most economic price, we consider such hazards as tsunamis and earthquakes. Recently, In December’s tsunami in the Indian Ocean, an estimated 250,000-300,000 people were killed or are still missing, while millions of lives have been upturned, socially and economically, by its impact. A main reason for theRead MoreThe Tragedy Of The West Coast Earthquake1302 Words   |  6 PagesWest Coast Earthquake The west coast can be split in half! There is no doubt that the west coast is aware of the monstrous earthquake that will happen in the near future, but unfortunately as a community we are not prepared for what is yet to come. California is right in the middle of the San Andreas fault line, therefore the whole state will be hugely affected by the upcoming earthquake. Thus, making it important for the state to prepare what is coming ahead. As a citizen of California, itRead MoreNatural Hazards are Rarely Completely Natural Essay991 Words   |  4 PagesNatural Hazards are Rarely Completely Natural Throughout the world, natural hazards are a frequent occurrence. They come in the forms of hurricanes, earthquakes, volcanic eruptions, and floods, to name but a few. On a range of scales they create disaster, destruction, loss of life and of livelihood. Natural processes have occurred in the natural environment for millions of years. They are events that happen naturally, e.g. blizzards and floods. A natural process onlyRead MoreThe Effects Of Climate Change On Natural Disasters1393 Words   |  6 Pagesthe Earth’s surface, which, in turn, dramatically increase the climate. Climate change has many consequences including various natural disasters such as earthquakes, hurricanes, volcanic eruptions, and storms. Recently, a link has been drawn between the increase in global warming and recent hurri-cane activity in the Atlantic Ocean. Hurricanes have always been a major concern for those living on the coast, but research has shown that global warming is only making them worse. Due to climate changeRead MoreReducing the Impact of Natural Disasters868 Words   |  4 PagesNatural Disasters are unfortunate events that can occur at any moment, anywhere in the world and have a huge effect on the landscape and the society being hit. Natural Disasters can occur due to the many natural causes such as earthquakes, hurricanes, tsunamis, floods, cyclones, landslides or due to some man-made causes such as forest fires or the use of nuclear weapons. Civil Engineering structures such as buildings, bridges, roads, dams, reservoirs, levees and other structures are severely damagedRead MoreAlso, Yumiko Has A Heightened Sense Of The World Around1492 Words   |  6 Pagesto control what happened to her duri ng the earthquake. By noticing every minute detail about the world around her in the future, she may be able to notice the beginnings of an earthquake in order to hide or protect herself. The descriptive nature ties back into her control of the world and providing her with a thorough description of her world so that she never loses another part of it. On the contrary, many of the narratives of children from Hurricane Katrina do not question the event nor struggleRead MoreJamaica Is The Country Of Jamaica1125 Words   |  5 Pagesenvironmental concern. The 3 negative attributes that make of this land are hurricanes, earthquakes, and the human activities. Kingston is commonly prone to many natural hazards. Most people probably wouldn’t know this because it’s not extremely often that we hear about these disasters happening there. Because this specific island is located directly in the hurricane belt they consequently experience many hurricanes. The hurricane belt is a part of the Atlantic Ocean. This area can be found in the northern

The Violent And Perverse System Of Human Trafficking

Slavery has been around for ages. There has always been someone forcing others to do their will. But slavery drags on in modern times, especially today. Modern day slavery, otherwise known as human trafficking, is defined by Encyclopedia Britannica as â€Å"...the illegal transport of individuals by force or deception for the purpose of labor, sexual exploitation, or activities in which others benefit financially† (â€Å"Human†). Slavery is not an issue of the past. It has waxed and waned throughout history, and will never cease unless something is done to stop it. Human trafficking is a serious issue in the world, the United States, and even in Iowa. The violent and perverse system of human trafficking is a worldwide system. People who are†¦show more content†¦To keep their victims from escaping, traffickers employ terroristic threats. They may threaten to deport them, take their (false) travel documents or hurt their families (â€Å"Human†). Overall, human trafficking, in essence, is a brutal industry. Since human trafficking is such an unjust thing, many, including the United States, have risen to combat it. In the 1990s there was a surge of human trafficking cases worldwide. Years later in 2005, the Georgetown Journal of International Affairs published an article about the fight against human trafficking. They noted in their article that numerous non-governmental organizations (NGOs) were formed in order to combat this surge of modern day slavery (Coonan). The United Nations also became involved in the 1990s. They treated human trafficking mainly as a law enforcement issue and so began forming what would later be called the UN Convention Against Transnational Organized Crime (the Convention) (Coonan). The Convention is not centered around lobbying and human rights groups, but on law enforcement and crime prevention. Therefore the crime must be defined. A daughter document to the Convention, the The UN Protocol to Prevent, Sup press, and Punish Trafficking in Persons, Especially Women and Children (the Protocol), has done this. The Protocol has been particularly important for fighting human trafficking because of two reasons: organizations which signed the treaty were required to criminalize and prosecute

Paper on “Night” by Elie Wisel Free Essays

Elie’s Spiritual Journey In Elie Wisel’s Night, Elie goes through an incredible spiritual change. In the beginning of his book he is striving to become the most devoted Jew he can. This is illustrated by his â€Å"crying because something inside me felt the need to cry† as he was praying in the temple. We will write a custom essay sample on Paper on â€Å"Night† by Elie Wisel or any similar topic only for you Order Now His devotion to Judism is also shown by his desire to study the Kabbalah. When his father discourages him from studying this â€Å"world of mysticism† Elie begins looking for his own teacher, and he finds Moishe the Beadle. Moishe helps Elie see why he prays and guide him in the teaching of the Kabbalists. One of the first times Elie’s faith is tested is when he first gets to Birkenau and sees the crematorium. There people are expecting death yet his father says â€Å"May His name be celebrated and sanctified. † Elie gets mad at his father for saying this, because Elie had an expectation from his devotion to Judism. He expects to have a long life with minimal trials thanks to his devotion. However, when his faith is tested he says: â€Å"For the first time I felt anger rising within me. Why should I sanctify His name? The Almighty and terrible Master of the Universe, chose to be silent. What was there to thank him for? † This shows he is disappointed in God. The Bible says â€Å"give thanks in all circumstances, for this is God’s will for you in Christ Jesus† (1 Thessalonians 5:18) Elie’s attitude is not thankful and even hating. We see that Elie also feels like God has left Elie and the Jews. In chapter 4 a young boy is hanged from the gallows. As he slips in and out of death someone says: â€Å"For God’s sake, where is God? † Elie says â€Å"Where He is? This is where – hanging here from this gallows. † Elie now believes God is dead or has forgotten about His people. His response shows that he has begun to totally disregard God, and even question himself as well as his faith. Elie is upset that God is allowing the Jews to be slaughtered. â€Å"You have betrayed (the inmates) allowing them to be tortured, slaughtered, gassed, and burned! What do they do? They pray before you! They praise your name! † This statement from chapter 5, during Rosh Hashanah, shows that Elie is definitely mad at God for letting the Holocaust happen. The next two paragraphs show how Elie’s faith has been shattered. â€Å"I knew my sins grieved the Almighty so I pleaded for forgiveness. . . But, now I no longer pleaded for anything. . . I was the accuser, God the accused. † These two statements reveal that Elie feels the power of the Holy Spirit to ask for forgiveness, yet he ignores it. He chooses instead to accuse God and to block out His voice. Despite all these times when he has denied God, Elie still begins his Nobel Peace Prize speech with a prayer. He goes on to talk about a small boy (him) that has emerged from the Kingdom of Night, the Holocaust. He said â€Å"A young Jewish boy discovered the Kingdom of Night. I remember his bewilderment, I remember his anguish. It all happened so fast. Elie also talks about his Judism. He tells everyone that his â€Å"First response is to Jewish fears. † He wants everyone to know that he will not stand by as his people are persecuted. As he draws his speech to a close he says, â€Å"Should Israel lose but one war, it would mean her end and ours as well. But I have faith. † This comment as well as his enti re speech, shows that Elie has, perhaps, restored his faith in God, despite his bitterness. However, only God knows his heart. Only God knows what that little boy crying in the temple went through, as he traveled through the Kingdom of Night. How to cite Paper on â€Å"Night† by Elie Wisel, Essay examples

Should Having Tattoos Affect What Kind of Job You Get free essay sample

Most tattoo artists wont tattoo your hands or neck just out of moral obligation. Many say, â€Å"We dont want you coming back later complaining about how you cant find a job because you got a tattoo up on your throat. Tattoos are becoming more common, and more acceptable. Some tattoos might not affect your job, but it is still something to consider. You might be working for a bank or some other professional company that doesnt want to be represented by a tattooed, bleached, spikey, colored hair person. So really consider what your future career will be before you get a tattoo done on your forearm, hands, neck or any other places that are not as easily covered up. Especially a large, noticeable one could definitely hinder your potential to get a job as a grade school teacher for sure! First impressions speak volumes, and tattoos may transmit the wrong message to your possible employer. We will write a custom essay sample on Should Having Tattoos Affect What Kind of Job You Get? or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page I vote no. Tattoos are irreversible (removing them is painful, expensive and doesnt fully work anyways) and most of the time a turn-off to employers. Also many job companies can judge you for your tattoos, so it can affect their choice of hiring you for the job you’re applying for. Most people could disagree to the opinion of others that say you shouldn’t be able to get any job with a tattoo that is visible, large, represents a bad thing ect.

Susceptibility of women and Aboriginal people to poverty in Canada

The Hillsborough disaster Essay Essay Example

The Hillsborough disaster Essay Essay Example The Hillsborough disaster Essay Essay The Hillsborough disaster Essay Essay The Hillsborough catastrophe was an incident that occurred on 15 April 1989 at the Hillsborough bowl in Sheffield. England. during the FA cup semi-final lucifer between Liverpool and Nottingham Forest association football nines. The crush resulted in the deceases of 96 people and hurts to 766 others. The incident has since been blamed chiefly on the constabulary. The incident remains the worst stadium-related catastrophe in British history and one of the world’s worst association football catastrophes. association football nines used to contend the semi-final of the FA Cup at a impersonal locale. and in 1989 Hillsborough was selected by the association football. While opposing protagonists were segregated in the bowl. Liverpool fans were allocated the Leppings Lane base. reached by a limited figure of turnstiles. Entry to the land was slow due to the few decrepit turnstiles available to the Liverpool fans which caused unsafe overcrowding outside the land before kick-off. In an effort to ease force per unit area outside the land. Chief Superintendent Duckenfield ordered an issue gate to be opened. The opened issue gate led to a tunnel marked â€Å"Standing† which led straight to the two already overcrowded enclosures ( pens ) . In old old ages the tunnel had been closed off by constabulary when the two cardinal pens were full. nevertheless on this juncture the tunnel was unmanned. The resulting inflow of protagonists caused suppression and some fans climbed over side fencings or were lifted by fellow protagonists onto the base above to get away the crush. Moments after kick-off. a crush barrier broke and fans began to fall on top of each other. The game was stopped after six proceedingss. To transport away the injured. protagonists tore down advertisement billboards to utilize as stretchers and exigency services were called to supply aid. Of the 96 people who died. 14 were admitted to infirmary. When the FA Chairman visited the Control Box to happen out what had happened. Chief Superintendent Duckenfield told a ‘disgraceful prevarication that the protagonists had â€Å"rushed† the gate. The 1990 functionary enquiry into the catastrophe. the Taylor Report. concluded â€Å"the chief ground for the catastrophe was the failure of constabulary control. The findings of the study resulted in the riddance of standing patios at all major football bowls in England. Wales and Scotland. On the twentieth day of remembrance of the catastrophe. authorities curate Andy Burnham called for the constabulary. ambulance and all other public bureaus to let go of paperss which were non made available to Lord Justice Taylor in 1989. This action led to the formation of the Hillsborough Independent Panel. which in September 2012 concluded that no Liverpool fans were responsible for the deceases. and that efforts had been made by the governments to hide what happened. including the change by constabulary of 116 statements associating to the catastrophe. The facts in the study prompted immediate apologies from Prime Minister David cameron ; the Chief Constable of South Yorkshire Police Chairman David Bernstein and Kelvin Mackenzie. then-editor of The Sun. for their organisations’ several functions. In September 2012. the Hillsborough Independent Panel concluded that up to 41 of the 96 human deaths might hold been avoided had they received prompt medical intervention. The study revealed â€Å"multiple failures† by other exigency services and public organic structures which contributed to the decease toll. In response to the panel’s study. Attorney General for England and Waless. Dominic Grieve MP. confirmed he would see all the new grounds to measure whether the original inquest finding of facts of inadvertent decease could be overturned. On 19 December 2012. a new inquest was granted in the High Court. to the alleviation of the households and friends of the Hillsborough deceased. 1. Examination of Evidence associating to the Hillsborough football bowl catastrophe. Lord Justice Stuart-Smith. February 1998. Page 83. hypertext transfer protocol: //www. southyorks. constabulary. uk/sites/default/files/STUART 2. Conn. David ( 17 April 2009 ) . â€Å"Football: David Conn on Hillsborough† . The Guardian. Retrieved 12 September 2012. 3. ^ Eason. Kevin ( 13 April 2009 ) . â€Å"Hillsborough: the catastrophe that changed football† . The Times ( UK ) . Retrieved 1 October 2009.

Chapter 1-3 questions Assignment Example | Topics and Well Written Essays - 500 words

Chapter 1-3 questions - Assignment Example Historians show that immediately after the end of the threat to England, the English nationalists obtained freedom and began growing and enforcing their roots. Accordingly, a section of the Englishmen who liked the queen threw their support for the Church of England but hated Catholics, majority of whom were from Spain. However, later attempts to stop the expansion of the English only served to promote the establishment of the English culture and pride (Brands et al., 2012). The Puritans decided to leave England and migrate to North America because they wanted to settle in a place where they could be free to practice their religion without interference. This is because they were strongly opposed to the liturgy and rituals of the Catholicism that was being imposed on them by the Church of England (Brands et al., 2012). The chaos that was experienced during the New Jersey settlement occurred due to two main factors. Firstly, the chaos emerged due to rivalry between Swedes and the Dutch over the fur trade. Secondly, the chaos erupted during the settlement following the New York governors move to assign lands to many Puritan groups unaware of the existence of Carteret and Berkeley proprietorship (Brands et al., 2012). The Barbadians background as agriculturalists contributed significantly to the development of the Carolinas. The Barbadians introduced the concept of sugarcane plantation to the Carolinas, which not only employed many of the residents, but also acted as a source of livelihood for the Carolinas (Brands et al., 2012). Life for women in the 17th century New England was difficult are required perseverance. Historians show that women of the time lived in deplorable conditions characterized by poor diet, illnesses and that childbearing was constant as women were expected only to bear children., Women of the time were also had to do hard work all day long. At the same time, women of the time had no right to choose a husband for themselves.

Investment Law Essay Example | Topics and Well Written Essays - 4000 words

Investment Law - Essay Example In some countries including United Kingdom, money laundering would be treated as a severe crime and persons indulged in money laundering would be punished strictly. It is not necessary that money laundering is restricted to only organized crime, it may be employed to create new assets or to increase the present assets illegally so that it would hamper the national economic growth rate of any nation in terms of gross domestic product3. The measures which lead to tax manipulations and faulty http://74.125.153.132/search?q=cache:WDGICRzCIJoJ:www.unodc.org/pdf/convention_1988_en.pdf+vienna+convention+against+illicit+traffic+innarcotic+Drugs+and+psychotropic+substances(1988)&cd=1&hl=en&ct=clnk&gl=in As discussed earlier, money laundering may be operated by different agencies or persons ranging from private individuals to terrorists at both national and global levels. The main concern of the society now a days is the role of money laundering played in strengthening the organization and financial health of terrorist outfits which is highly dangerous for establishing world peace4. There are sympathisers operated at various levels from the society who support terrorists by financing them through illegal means which also come under money laundering. Hence there is a strong connecting link between money laundering and terrorist financing. The alarming thing before us at this moment is the increasing magnitude of the problem of money laundering. Various types of processes are involved in terrorist financing terrorists and money laundering is most important means out of these processes. People from regular streams like employees, scientists and artists may be involved in online transactions which finance the terrorist outfits. Hawala is one of the most important means through which money is laundered. Terrorist organizations like Alkhaida got tremendous benefit through hawala transactions in building their

Genetic Mutations Result In Faulty Proteins

Genetic Mutations Result In Faulty Proteins The DNA sequence codes for a particular gene which is then copied into a protein sequence code. Protein is found in every cell in human body and has a vital role in cell growth and tissue repair. The amino acids are the building blocks of proteins which are arranged in a specific order to determine the proteins shape and function. The incorrect amino acid sequence leads to harmful consequences because it can lead to the formation of faulty proteins which can cause disruption in metabolic and regulatory pathways which cause genetic disorders (1). Genetic mutation is a change in genomic sequence which encodes DNA. It can be either inherited or somatic mutation. Somatic mutations are introduced either during DNA replication or when the DNA repair process fails. Agents which damage DNA are frequent carcinogens. Most carcinogenic agents are mutagens. There are two classes of mutations caused by mutagens. The first class is spontaneous mutations caused by depurination, deamination and demethylation(3). The second class is induced mutations caused by ionizing radiation,chemical mutagens and ultra violet radiation(3). Mutation during DNA replication Before cell divides, cell duplicates its entire DNA sequence. To start DNA replication, the DNA helicase separates the DNA molecule into two strands. Then DNA polymerase copies each strand of DNA in order to create two double-stranded DNA molecules. Somatic mutation occurs when this DNA polymerase makes an error in copying which takes place once every 100,000,000 bases (4). Mutation effects Single base substitution: The consequences of single base substitution mutation depend on the location of the protein which can lead to either silent mutation, missense mutation or a non-sense mutation. Silent mutations are those which dont produce any change in an amino acid sequence of a protein. They occur in that region that either doesnt code for a protein or doesnt alter the final sequence of amino acid chain. For example GCA codon turns into GCG codon as in result of single nucleotide replacement because both GCA and GCG codons mean arginine in mRNA (8). Missense mutations involve a change in a single nucleotide to cause substitution of a different amino acid. This can result into a non-functional protein. Sickle cell anemia is an example of missense mutation where CTC in the DNA sense strand specifies glutamate residue get altered with GUG in the mRNA which results in a Valine residue in the protein causing sickle-cell anemia (8). Non-sense mutations are those which results in a premature stop codon leading to the formation of a non-functional protein. An example for non-sense mutation is a single nucleotide replacement from C to T in codon CAG which forms a stop codon TAG. This incorrect sequence causes the shortening of protein (8). Frameshift mutation: This mutation is the result of an insertion or a deletion of one or more nucleotides from the DNA sequence but not in multiples of three because bases in set of three forms a codon which provides the code for an amino acid sequence of the protein. So as DNA polymerase read the triplet nature of codon so an insertion or a deletion can disrupt its reading frame which results into a completely different translation done by the DNA polymerase (8+6). Chromosome mutation: Any change either in structure or arrangement of chromosomes is a chromosome mutation which frequently occurs in meiosis during crossing over. The different types of chromosome mutation are:- Translocation: In this mutation, a piece of one chromosome gets transferred to a non-homologous chromosome. For example when translocation between chromosomes 9 and 22 takes place, an abnormal gene forms which codes for an abnormal faulty protein resulting the development of leukaemia (8). Inversion: During this mutation, a DNA region on a chromosome flips its orientation leading the formation of an abnormal gene which then codes for a faulty abnormal protein. Deletion: In this mutation, a chromosome section gets deleted which results in the loss of genes (6). Duplication: During this mutation, some genes get duplicate and get read twice by the DNA polymerase on the same chromosome resulting in the formation of a faulty abnormal protein (6). Non-disjunction: This is when chromosomes dont separate successfully to opposite poles at anaphase stage during meiosis which allows the presence of an extra chromosome in one of the daughter cells. Downs syndrome is an example of non-disjunction which occurs in chromosome 21 of a human egg cell (8). Removal of faulty proteins In eukaryotic cells, faulty proteins are recognized and degraded very rapidly in cells to prevent any harmful consequences. The two major faulty protein destruction pathways are:- Ubiquitin-proteasome pathway for faulty intracellular proteins: In the case of formation of faulty proteins which are defective get ejected into the proteasome from the endoplasmic reticulum through channels called retrotranslocons. Proteasome is a large multi-catalytic protein complex found in all eukaryotes which is located in nucleus and cytoplasm. It is responsible to degrade faulty intracellular proteins through proteolysis(2). The enzymes which carry out proteolysis are known as proteases. Those intracellular proteins which need to go under degradation get tagged with another small protein called ubiquitin(2). Ubiquitin binds to the amino group of the side chain of a lysine residue. This tagging process is catalyzed by ubiquitin ligase. Once the protein gets tagged,a signal gets released to other ligases allowing more ubiquitin molecules to attach to form a poly-ubiquitin chain. Poly-ubiquitin chain then bound by the 26s proteasome complex which leads to the degradation of tagged protein(7). Ubiquitin does get released which that can be reused in next cycle. However ATP is used for the attachment of ubiquitin and for the degradation of tagged proteins (5). Lysosomal proteolysis for faulty extracellular proteins: Lysosomes are membrane-enclosed cellular organelles in animals containing digestive enzymes and proteases. They have important roles in cell metabolism including the digestion of extracellular proteins taken up through endocytosis. So during this protein degradation pathway, the protein is uptaken by lysosomes through the formation of vesicles derived from endoplasmic reticulum called autophagosomes. Then these autophagosomes fuse with lysosomes so in result the digestive lysosomal enzymes digest their contents (5).

Hamlet Essay -- essays research papers

Contrast Between Hamlet, Laertes And Fortinbras Hamlet (prince of Denmark) can be greatly compared to Laertes (son of a noble), and Fortinbras (prince of Norway) in the play. They all are very similar but yet different at the same time. They all had love and respect for their fathers and felt the need to avenge their deaths, which all were brutally killed. All three believed that the murderers had dishonoured their fathers as well as themselves. They all reacted and took different approaches in attempt to restore honour in their families. Hamlet seems to be the one who lets things dwell in his mind before taking any action or making an attempt at trying to get on with his life. After the death of his father he becomes depressed and gradually becomes enraged with his mother’s immediate marriage to his uncle Claudius. He was lead to believe his father died of natural cause but he became aware of the murderer when his father’s ghost appeared to him. When Hamlet learns the truth of his father’s murder, he cries, but promises action, though he delivers none. He says â€Å"Haste me to know’t, that I, with wings as swift as meditation or the thoughts of love, may sweep to my revenge.† (Act 1, Sc. 5, 29-31). At the end of the scene he says â€Å"The time is out of joint: O cursed spite, that ever I was born to set it right!† (Act 1, Sc. 5, 188-189). This shows that he is no longer in such a rush to avenge his father’s death by killing his uncle Claudius. The appearance of...

Eagle Scout Essay

  Hello everybody. To start off I would like to say thank you to everyone here for coming, because if it wasn’t for all of you this day wouldn’t be so special. I would like to give a special thanks to my parents for getting me involved in boy scouts, mr.mac, mr.beteyyman, mr.deangles, and all the other leaders for leading my troop, and the scouts that helped me complete my Eagle Scout project. From the start to the end boy Scouts has shaped me as the person that I am today, and without Boy Scouts I wouldn’t be the person that I am. Not knowing where Scouting would lead me, I joined the troop due to many interests such as having fun. It all started when I was about 7 years old and walked into the elks lodge to have my first meeting as a tiger scout. From tiger scouts on I decided that I really liked the scouting experience and would continue on the whole journey. Racing boats in the rain gutter regatta, and racing cars in the pine wood derby were just a few of t he events early on. Time had passed earning belt loops, camping some, and learning wilderness survival tips, and before I knew it Webloes 2 was completed and I had a decision to make. I decided that I would cross over to boy Scouts and shoot for the goal of my Eagle Scout. Anxiously waiting at the table for my name to called, a member from the order of the arrow dressed up as an American Indian came over to me and walked me to the front of the building and over the bridge. I was then welcomed by the boy Scouts and given a troop 2540 handkerchief and hat. I decided that I would be one of the kids to go to all the meeting, trips, and scouting events.   One of my very first memories was the camping trip to rickets Glenn in Pennsylvania. The scenery of waterfalls and hiking through the wilderness hit me immediately that I loved the idea of camping and couldn’t wait to go on the next trip. As time progressed learning how to cook, pitch tents, tie knots, first aid, and physical fitness, I was moving through the ranks very quickly. Some events such as community service taught me to always give back to the community, and to take leadership roles in the troop showed me how to be a good leaders and not a follower. My most memorable camping trips were the 2 out of the 4 high adventure trips that I completed. The National Jamboree in Arlington Virginia celebrated the 100 years of scouting, and the most memorable part of this trip was getting Shaun Whites autograph. Hiking through the wilderness at Philmont Scout Reservation was an amazing espicially hiking up mt.baldy and catching mini bears in our bear bags to  pass time at cam p. Boy Scouts has meant so much to me and has helped me discover what I like to do through the 27 merit badges that I earned over the years. Getting my eagle scout was a long and memorable journey and has helped me become who I am today. Thank you

MAnaging Conflict Essay - 618 Words

Managing Conflict What is conflict? Conflict is a natural disagreement resulting from individuals or groups that differ in attitudes, beliefs, values or needs. It can also originate from past rivalries and personality differences. Other causes of conflict include trying to negotiate before the timing is right or before needed information is available. Causes of conflict. 1.nbsp;nbsp;nbsp;nbsp;nbsp;Lack of communication. There is a lack of communications. Failure to share ideas and feelings (between wife and husband for example) allows the other person to quot;fill in the gap.quot; We quot;read inquot; what we think the other person will say or anticipate how the other person will respond. Then, we often suspect negative things†¦show more content†¦Lack of agreement about quot;whos in chargequot; or quot;how we are going to get things donequot; in any situation can be a source of conflict. For example, if one parent in a family expects democratic decision-making (all members have input) and the other wants to be the boss (do it my way), they may not be able to resolve honest differences of opinion. Then when differences exist, they become sidetracked into a hassle over who will decide or whose opinion is going to be accepted as the quot;rightquot; one. The resulting conflict becomes a quot;win-losequot; struggle. 4. Change causes disequilibrium. While change is considered to be a quot;givenquot; for people working and living together, another quot;givenquot; is that people prefer secure, predictable patterned responses to the unknown. When changes occur abruptly and unpredictably, conflict may follow (e.g. The wife comes home from her college class one night and says quot;I want a divorce.quot;). Forces may have been at work for a long time to cause such a change, but it appears suddenly and provokes anger, anxiety and confusion. How to resolve conflict 1.nbsp;nbsp;nbsp;nbsp;nbsp;Proper communication Proper communication should be facilitated so as to avoid rumours and gossip. This prevents people from thinking negative thoughts especially when they don’t know what is happening. 2. Proper Leadership and effective decision-making. In an organization there should be a proper structureShow MoreRelated managing conflicts and negotiation Essay544 Words   |  3 Pages Managing Conflict and Negotiations In week one, the class read and discussed topics related to problem-based learning and managing conflict and negotiation. Also, the Learning Team handbook and tools were introduced and teams were assigned. The required readings, class discussions and sharing of experiences were valuable in learning more about these topics. The 9-step problem-solving model is a valuable, systematic tool used to identify the real problem and make an intelligent decision. This processRead MoreManaging Conflict and Negotiating2855 Words   |  12 PagesManaging Conflict and Negotiating Wherever choices exist, there is potential for disagreement. No matter what we major in, no matter where our career path takes us, inevitably, we all encounter conflict in some form. In todays highly competitive society, for an organization to be truly successful, it is imperative that the organizations leadership understands conflict and deals with it in the best way possible. Managements ability to recognize and accept divergence and their ability to employRead MoreEssay on Managing Conflict2419 Words   |  10 PagesManaging Conflict The ability to manage conflict is undoubtedly one of the most important skills a manager needs to possess A study of middle- and top-level executives revealed that the manager spends approximately 20% of his or her time dealing with conflict. In most management development programmes; conflict management was being more important than decision making, leadership or communication. DEALING WITH CONFLICT Concept Definition Want Desire for something Goal DesiredRead MoreReflective Essay On Managing Conflict2544 Words   |  11 PagesIntroduction Conflict is inevitable. Put people with different experiences, priorities, and skills together, and you are bound to have conflict. It is a fundamental dynamic of human nature. How one deals with conflict is the results of core personality traits, experiences that have become schemas, commitment to ideas and training. I’ve been fortunate to have wonderful early experiences that have seeded my ability to manage conflict as well as exposure through fabulous training initiatives. Even withRead MoreConflict Management : The Styles And Outcomes Of Managing Conflict1541 Words   |  7 PagesConflict Management: The Styles and Outcomes of Managing Conflict in Modern Society Corbin Metz University of Oklahoma Communication is an obligatory aspect for the existence of human life. In our society today, conflict is managed through various styles, some leading to more positive outcomes than others. Although many people attempt to not confront conflict and rather avoid the issue, which may cause it to worsen, it is an aspect that every person willRead MoreManaging Conflict Essay example1527 Words   |  7 Pagesresolve a conflict. People do experience conflict in their lives. There has always been a lot of interest in how to manage conflict once it appears in the open, and that is important. What is not so common is a concern for preventing unnecessary conflict, so it does not start in the first place. Managers are capable of using all five resolutions skills to deal with conflict in the workplace. Organizations of all types need good managers in order to survive when dealing with conflicts thatRead MoreManaging Conflict Through Communication Essay1208 Words   |  5 Pagesbasis, and in a confined space. There’s going to be conflicts in every environment especially in the workplace where most people spend the greater part of the day. Conflict is hard to define because every situation is different, it could be either tangible or intangible in the case of feelings. Conflict resolution is a task not easily handled, and it can be really disparaging if not properly taken care of when it is identified. Workplace conflict can be caused by various factors, and can cause aRead MoreM3.14 Managing Conflict in the Workplace Essay1875 Words   |  8 PagesREFLECTIVE REVIEW - M3.14 MANAGING CONFLICT IN THE WORKPLACE |Centre Number |Centre Name | |Candidate Registration No |Candidate Name | |Please use the headings shown below |Assessment Criteria | | Read MoreJan Ken: Managing Conflict in Relationships Essay1691 Words   |  7 Pagesï » ¿ Jan Ken: Managing Conflict in Relationships Unit 9 Assignment Marie Holloway Kaplan University Author Note: This research is being submitted on March 11, 2014 for Mark Lambertson’s CM206 Interpersonal Communications course. Q #1: Using the chapters on language and emotions to help frame your answer, suggest two ways that Ken could open this conversation more productively, beyond clearly expressing his emotions and using â€Å"I† language. Ken could have usedRead MoreManaging Conflict And Organizational Change924 Words   |  4 PagesManaging conflict and the importance of a vision/mission in an organization are two important topics in our course of Leadership and Organizational Change. In this paper we tried to analyze the connection between these two important aspects of leadership. Our analysis and our interviews of leaders have supported and amplified what we have learnt in class. As we have seen during this course, working in a team can often lead to conflicts. In particular there are three types of conflicts that we described